Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies.

Chew, Hui Yi; De Lima, Priscila O; Gonzalez Cruz, Jazmina L; Banushi, Blerida; Echejoh, Godwins; Hu, Lingbo; Joseph, Shannon R; Lum, Benedict; Rae, James; O'Donnell, Jake S; Merida de Long, Lilia; Okano, Satomi; King, Brigid; Barry, Rachael; Moi, Davide; Mazzieri, Roberta; Thomas, Ranjeny; Souza-Fonseca-Guimaraes, Fernando; Foote, Matthew; McCluskey, Adam; Robinson, Phillip J; Frazer, Ian H; Saunders, Nicholas A; Parton, Robert G; Dolcetti, Riccardo; Cuff, Katharine; Martin, Jennifer H; Panizza, Benedict; Walpole, Euan; Wells, James W; Simpson, Fiona.

Cell ; 180(5): 895-914.e27, 2020 03 05.

Artigo em Inglês | MEDLINE | ID: mdl-32142680

2.

Caveolae: Structure, Function, and Relationship to Disease.

Parton, Robert G.

Annu Rev Cell Dev Biol ; 34: 111-136, 2018 10 06.

Artigo em Inglês | MEDLINE | ID: mdl-30296391

3.

Is endocytosis by caveolae dependent on dynamin?

Parton, Robert G; Taraska, Justin W; Lundmark, Richard.

Nat Rev Mol Cell Biol ; 2024 Apr 22.

Artigo em Inglês | MEDLINE | ID: mdl-38649754

4.

FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors.

Nguyen-Dien, Giang Thanh; Kozul, Keri-Lyn; Cui, Yi; Townsend, Brendan; Kulkarni, Prajakta Gosavi; Ooi, Soo Siang; Marzio, Antonio; Carrodus, Nissa; Zuryn, Steven; Pagano, Michele; Parton, Robert G; Lazarou, Michael; Millard, S Sean; Taylor, Robert W; Collins, Brett M; Jones, Mathew Jk; Pagan, Julia K.

EMBO J ; 42(13): e112767, 2023 07 03.

Artigo em Inglês | MEDLINE | ID: mdl-37161784

5.

Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG-Syt1-SV2 plasma membrane nanocluster for synaptic vesicle entry.

Joensuu, Merja; Syed, Parnayan; Saber, Saber H; Lanoue, Vanessa; Wallis, Tristan P; Rae, James; Blum, Ailisa; Gormal, Rachel S; Small, Christopher; Sanders, Shanley; Jiang, Anmin; Mahrhold, Stefan; Krez, Nadja; Cousin, Michael A; Cooper-White, Ruby; Cooper-White, Justin J; Collins, Brett M; Parton, Robert G; Balistreri, Giuseppe; Rummel, Andreas; Meunier, Frédéric A.

EMBO J ; 42(13): e112095, 2023 07 03.

Artigo em Inglês | MEDLINE | ID: mdl-37226896

6.

Building endocytic pits without clathrin.

Johannes, Ludger; Parton, Robert G; Bassereau, Patricia; Mayor, Satyajit.

Nat Rev Mol Cell Biol ; 16(5): 311-21, 2015 05.

Artigo em Inglês | MEDLINE | ID: mdl-25857812

7.

Constitutive formation of caveolae in a bacterium.

Walser, Piers J; Ariotti, Nicholas; Howes, Mark; Ferguson, Charles; Webb, Richard; Schwudke, Dominik; Leneva, Natalya; Cho, Kwang-Jin; Cooper, Leanne; Rae, James; Floetenmeyer, Matthias; Oorschot, Viola M J; Skoglund, Ulf; Simons, Kai; Hancock, John F; Parton, Robert G.

Cell ; 150(4): 752-63, 2012 Aug 17.

Artigo em Inglês | MEDLINE | ID: mdl-22901807

8.

ORP2 Delivers Cholesterol to the Plasma Membrane in Exchange for Phosphatidylinositol 4, 5-Bisphosphate (PI(4,5)P₂).

Wang, Huan; Ma, Qianli; Qi, Yanfei; Dong, Jiangqing; Du, Ximing; Rae, James; Wang, Jue; Wu, Wei-Feng; Brown, Andrew J; Parton, Robert G; Wu, Jia-Wei; Yang, Hongyuan.

Mol Cell ; 73(3): 458-473.e7, 2019 02 07.

Artigo em Inglês | MEDLINE | ID: mdl-30581148

9.

Defensive-lipid droplets: Cellular organelles designed for antimicrobial immunity.

Safi, Rémi; Sánchez-Álvarez, Miguel; Bosch, Marta; Demangel, Caroline; Parton, Robert G; Pol, Albert.

Immunol Rev ; 317(1): 113-136, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-36960679

10.

Cells respond to mechanical stress by rapid disassembly of caveolae.

Sinha, Bidisha; Köster, Darius; Ruez, Richard; Gonnord, Pauline; Bastiani, Michele; Abankwa, Daniel; Stan, Radu V; Butler-Browne, Gillian; Vedie, Benoit; Johannes, Ludger; Morone, Nobuhiro; Parton, Robert G; Raposo, Graça; Sens, Pierre; Lamaze, Christophe; Nassoy, Pierre.

Cell ; 144(3): 402-13, 2011 Feb 04.

Artigo em Inglês | MEDLINE | ID: mdl-21295700

11.

Caveolae as plasma membrane sensors, protectors and organizers.

Parton, Robert G; del Pozo, Miguel A.

Nat Rev Mol Cell Biol ; 14(2): 98-112, 2013 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-23340574

12.

Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains.

Puthenveedu, Manojkumar A; Lauffer, Benjamin; Temkin, Paul; Vistein, Rachel; Carlton, Peter; Thorn, Kurt; Taunton, Jack; Weiner, Orion D; Parton, Robert G; von Zastrow, Mark.

Cell ; 143(5): 761-73, 2010 Nov 24.

Artigo em Inglês | MEDLINE | ID: mdl-21111236

13.

A synthetic organelle approach to probe SNARE-mediated membrane fusion in a bacterial host.

Ferreras, Soledad; Singh, Neha Pratap; Le Borgne, Remi; Bun, Philippe; Binz, Thomas; Parton, Robert G; Verbavatz, Jean-Marc; Vannier, Christian; Galli, Thierry.

J Biol Chem ; 299(3): 102974, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36738791

14.

Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic lipid and carbohydrate metabolism.

Keshvari, Sahar; Masson, Jesse J R; Ferrari-Cestari, Michelle; Bodea, Liviu-Gabriel; Nooru-Mohamed, Fathima; Tse, Brian W C; Sokolowski, Kamil A; Batoon, Lena; Patkar, Omkar L; Sullivan, Mitchell A; Ebersbach, Hilmar; Stutz, Cian; Parton, Robert G; Summers, Kim M; Pettit, Allison R; Hume, David A; Irvine, Katharine M.

Am J Physiol Endocrinol Metab ; 326(2): E149-E165, 2024 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-38117267

15.

Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth.

Goodall, Emily C A; Isom, Georgia L; Rooke, Jessica L; Pullela, Karthik; Icke, Christopher; Yang, Zihao; Boelter, Gabriela; Jones, Alun; Warner, Isabel; Da Costa, Rochelle; Zhang, Bing; Rae, James; Tan, Wee Boon; Winkle, Matthias; Delhaye, Antoine; Heinz, Eva; Collet, Jean-Francois; Cunningham, Adam F; Blaskovich, Mark A; Parton, Robert G; Cole, Jeff A; Banzhaf, Manuel; Chng, Shu-Sin; Vollmer, Waldemar; Bryant, Jack A; Henderson, Ian R.

PLoS Genet ; 17(12): e1009586, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-34941903

16.

Formation of retromer transport carriers is disrupted by the Parkinson disease-linked Vps35 D620N variant.

Cui, Yi; Yang, Zhe; Flores-Rodriguez, Neftali; Follett, Jordan; Ariotti, Nicholas; Wall, Adam A; Parton, Robert G; Teasdale, Rohan D.

Traffic ; 22(4): 123-136, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33347683

17.

Caveolae and the oxidative stress response.

Wu, Yeping; Lim, Ye-Wheen; Parton, Robert G.

Biochem Soc Trans ; 51(3): 1377-1385, 2023 06 28.

Artigo em Inglês | MEDLINE | ID: mdl-37248872

18.

SnapShot: caveolae, caveolins, and cavins.

Ariotti, Nicholas; Parton, Robert G.

Cell ; 154(3): 704-704.e1, 2013 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-23911330

19.

Modular transient nanoclustering of activated ß2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies.

Gormal, Rachel S; Padmanabhan, Pranesh; Kasula, Ravikiran; Bademosi, Adekunle T; Coakley, Sean; Giacomotto, Jean; Blum, Ailisa; Joensuu, Merja; Wallis, Tristan P; Lo, Harriet P; Budnar, Srikanth; Rae, James; Ferguson, Charles; Bastiani, Michele; Thomas, Walter G; Pardon, Els; Steyaert, Jan; Yap, Alpha S; Goodhill, Geoffrey J; Hilliard, Massimo A; Parton, Robert G; Meunier, Frédéric A.

Proc Natl Acad Sci U S A ; 117(48): 30476-30487, 2020 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-33214152

20.

Twenty years of traffic: A 2020 vision of cellular electron microscopy.